Persistent Bacterial Infections

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Offering an examination of persistent bacterial infections in the light of ecological and evolutionary principles, this important volume focuses on the principles of parasitism and commensalism and our ability to distinguish the two states. Throughout the volume, the authors explore the ways in which persistent infections differ from acute, self-limiting bacterial infections and how both differ from the nonpathogenic commensal state. The volume also addresses coevolution, host adaptation, natural selection, and other fundamental biological principles.

Valuable reading for investigators and advanced students in the field of bacterial pathogenesis.


Einband gebundene Ausgabe
Herausgeber James P. Nataro, Martin J. Blaser, Susanna Cunningham-Rundles
Seitenzahl 453
Erscheinungsdatum 01.05.2000
Sprache Englisch
ISBN 978-1-55581-159-4
Verlag Asm Pr
Maße (L/B/H) 26,5/17,7/2,9 cm
Gewicht 1052 g


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  • I. Introduction II. The Biology of Persistent Infection Microbial Mechanisms for Establishing Persistence - Antigenic Variation Microbial Mechanisms for Establishing Persistence - Privileged Intracellular Sites Microbial Mechanisms for Establishing Persistence - Avoidance of the Immune Response Mathematical Modeling of Persistent Infections The Natural History and Ecology of Commensal Human Flora Pathological Consequences of Commensalism Bacterial Infections in the Immunocompromised Host Immunologic Basis of Persistent Bacterial Infections III. Persistent Bacterial Pathogens Neisseria gonorrheae Chlamydia spp. Helicobacter pylori Borrelia spp. Pseudomonas aeruginose Infection in Cystic Fibrosis Patients Mycobacterial Infections Bartonella spp. Treponema pallidum IV. Pathogenesis of Persistent Clinical Syndromes Endocarditis Osteomyelitis/Septic Arthritis Abscesses Dental Plaque Biofilms and Device Infections